C60 fullerene as promising therapeutic agent for correcting and preventing skeletal muscle fatigue

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C60 fullerene as promising therapeutic agent for correcting and preventing skeletal muscle fatigue

BACKGROUND Bioactive soluble carbon nanostructures, such as the C60 fullerene can bond with up to six electrons, thus serving by a powerful scavenger of reactive oxygen species similarly to many natural antioxidants, widely used to decrease the muscle fatigue effects. The aim of the study is to define action of the pristine C60 fullerene aqueous colloid solution (C60FAS), on the post-fatigue re...

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C60 Fullerene as Promising Therapeutic Agent for the Prevention and Correction of Skeletal Muscle Functioning at Ischemic Injury

The therapeutic effect of pristine C60 fullerene aqueous colloid solution (C60FAS) on the functioning of the rat soleus muscle at ischemic injury depending on the time of the general pathogenesis of muscular system and method of administration C60FAS in vivo was investigated. It was found that intravenous administration of C60FAS is the optimal for correction of speed macroparameters of contrac...

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Complex of C60 Fullerene with Doxorubicin as a Promising Agent in Antitumor Therapy

The main aim of this work was to evaluate the effect of doxorubicin in complex with C60 fullerene (C60 + Dox) on the growth and metastasis of Lewis lung carcinoma in mice and to perform a primary screening of the potential mechanisms of C60 + Dox complex action. We found that volume of tumor from mice treated with the C60 + Dox complex was 1.4 times less than that in control untreated animals. ...

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ژورنال

عنوان ژورنال: Journal of Nanobiotechnology

سال: 2017

ISSN: 1477-3155

DOI: 10.1186/s12951-016-0246-1